Quarterly earnings came in at $747.0 million, or 64 cents per share, compared with $830.0 million, or 64 cents per share, a year earlier.
Sales fell 2 percent to $14.25 billion.
Analysts on average had expected a profit of 70 cents per share on revenue of $14.46 billion, according to Thomson Reuters I/B/E/S.
Shares of Lowe's closed at $27.87 on Friday on the New York Stock Exchange.
(Reporting by Ranjita Ganesan; Editing by Sriraj Kalluvila)
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