The S&P 500 and the Nasdaq posted their best daily percentage gains since December on Friday after an agreement by European leaders to stabilize the region's troubled banks, a pact that helped remove some of the uncertainty that has plagued markets.

"That is the major question. Can this fuel a longer-term rally? It can, but only to some degree if, over the weekend and the course of next week, we don't see any major push back or headlines that suggest that this deal is not going to happen," said Quincy Krosby, a market strategist at Prudential Financial.

"But I don't think this is a major game changer. I do, however, think that this is really the first time we got a relatively immediate answer to what they (the euro-zone leaders) are going to do about the issue."

Under pressure to prevent a catastrophic breakup of their single currency, euro-zone leaders agreed on Friday to let their rescue fund inject aid directly into stricken banks starting next year and intervene in bond markets to support troubled member-states.

They also pledged to create a single banking supervisor for euro-zone banks based around the European Central Bank in a landmark first step toward a European banking union that could help shore up struggling member Spain.

PARTY TIME

Wall Street's previous reaction to euro-zone bailout packages or other rescue plans had been somewhat muted. Initial gains would quickly disappear by the day's end as investors realized that there isn't a quick fix to the region's problems.

On Friday, it was a different story. The three major U.S. stock indexes jumped 1.5 percent to 2 percent shortly after the opening bell on news of the euro-zone agreement.

By the close, stocks ended at session highs with the major indexes up between 2 percent and 3 percent. The Dow Jones industrial average .DJI surged 277.83 points, or 2.20 percent, to end at 12,880.09. The Standard & Poor's 500 Index .SPX jumped 33.12 points, or 2.49 percent, to finish at 1,362.16. And the Nasdaq Composite Index .IXIC shot up 85.56 points, or 3.00 percent, to close at 2,935.05.

For the week, the Dow rose 1.9 percent, the S&P 500 advanced 2 percent and the Nasdaq gained 1.5 percent.

For the month, the Dow added 3.9 percent, the S&P 500 rose 4 percent and the Nasdaq climbed 3.8 percent.

But for the second quarter, the Dow dropped 2.5 percent, the S&P 500 slid 3.3 percent and the Nasdaq lost 5.1 percent.

Despite the weak second quarter, the three major U.S. stock indexes wrapped up the first half of the year with decent gains: The Dow was up 5.4 percent, the S&P 500 was up 8.3 percent and the Nasdaq was up 12.7 percent.

"The next question is whether the ESM/EFSF will have enough capital and assuming they don't, will the ECB chip in by giving it a bank license, thus leveraging its size. That is yet to be determined," said Peter Boockvar, equity strategist at Miller Tabak & Co in New York.

"For now, party on and turn that hourglass over as more time has been bought. But only the symptoms are being fought as the underlying disease of excessive debt and lack of growth still remains."

The leaders of the 17 European Union countries agreed on a series of short-term steps to shore up their monetary union and bring down the borrowing costs of Spain and Italy, seen as too big to bail out.

To that end, the euro zone's temporary European Financial Stability Facility (EFSF) and permanent European Stability Mechanism (ESM) rescue funds will be used "in a flexible and efficient manner in order to stabilize markets" to support countries that comply with EU budget policy recommendations, a joint statement said.

Any market reaction to further developments next week could be exaggerated by lighter-than-usual volume. Wall Street trading desks may be more sparsely populated because it will be a short week. The U.S. stock market will be closed on Wednesday, the Fourth of July, in observance of Independence Day. That could break any weekly momentum when Wall Street resumes trading on Thursday.

ALL EYES ON THE ECB

The market's focus shifts to the European Central Bank next week as investors wait to see whether it cuts interest rates to complement the measures taken by EU leaders to shore up banks and bring down borrowing costs for Spain and Italy.

Most economists polled by Reuters expect the ECB to cut borrowing costs on Thursday, July 5, at its meeting, which takes place against a darkening economic backdrop.

But internal resistance to the central bank reviving its bond-buying program remains high. The ECB has already loosened its collateral rules to make it easier for banks in Spain to access its funds.

"Investors have to be cautious because the market may be getting ahead of itself. We really don't have any details. The big question is still what direction the ECB takes next week," said Omer Esiner, chief market analyst at Commonwealth Foreign Exchange in Washington.

"It's (the EU deal) certainly not a silver bullet for the debt crisis, but the market is kind of acting like it is. It may set us up for another push down in the weeks ahead."

Stocks had enjoyed a run earlier this month on hopes that global central banks would announce additional measures to stimulate economic growth, which has been tepid.

On June 20, the Federal Reserve extended its "Operation Twist" program to sell short-term securities and buy longer-term ones to keep long-term borrowing costs down. But investors were disappointed when U.S. Federal Reserve Chairman Ben Bernanke, who spoke at a news conference after the Fed's two-day policy meeting, gave few hints that further monetary stimulus was imminent, denting hopes of cheap money in the equities market.

European bond yields will be closely watched next week. Madrid will auction three-year, four-year and 10-year bonds at a primary auction on Thursday in another big test for Spanish yields that are still not far below 7 percent.

France will sell between 7 billion and 8 billion euros in long-term bonds on Thursday.

Next week's data includes the Institute for Supply Management's U.S. manufacturing index and construction spending on Monday, followed by factory orders and June car sales on Tuesday.

After the holiday on Wednesday, investors will face a blitz of economic indicators. On Thursday, weekly jobless claims and mortgage data, ADP's private-sector payrolls report and the ISM's U.S. services-sector index will be released.

On Friday, the government's June nonfarm payrolls report will come out. Economists polled by Reuters have forecast a gain of 90,000 jobs, with the U.S. unemployment rate holding steady at 8.2 percent.

(Reporting by Angela Moon; Additional reporting by Steven C. Johnson; Editing by Jan Paschal)

• A Permanent Economic Emergency