The study of Washington state residents who underwent colon cancer treatment found that compared with older people, patients under age 50 had more than 50-times greater chances of selling or refinancing their homes, having their income drop 20 percent or more, going into debt or having to borrow money from friends and family to meet expenses.

Patients with household incomes below $30,000 were about eight times more likely to face those financial problems than those who were better off.

"I think most oncologists have heard these stories where people are spending a lot on their treatments," said Dr. Veena Shankaran, the study's lead author and an oncologist at the University of Washington. "These anecdotes are things we always hear in clinics and I wanted to get a broader sense of what's going on."

The study also found that most patients didn't discuss the cost of their treatments with their doctors, and some even skipped or refused treatment because of the price tag.

To gauge the financial impact of cancer treatment, Shankaran and her colleagues sent a survey to 555 adults living in various parts of Washington State and diagnosed with advanced colon cancer between 2008 and 2010.

The questionnaire asked about the participants' financial situation, whether or not they had insurance and about their treatments

Of the 284 people who responded, 104 reported at least one serious financial hardship related to their cancer treatment.

Shankaran told Reuters Health that they did not go into this analysis with any specific expectations. But, she added, "To have nearly 40 percent of patients have these major financial changes was quite surprising to us."

They speculate that those groups have less savings and other resources to fall back on when copayments and denied reimbursement claims start adding up.

Another 27 percent of the survey respondents described lesser financial impacts, including having to sell stocks or withdraw from savings or retirement accounts, or experiencing a drop in income of less than 20 percent.

The researchers found a small number of the respondents who skipped or refused treatment because of costs -- about five percent and seven percent, respectively.

In an accompanying editorial in the Journal of Clinical Oncology, Cathy Bradley, a health policy researcher at the Virginia Commonwealth University School of Medicine, in Richmond, says there are several ways for the health care system to avoid financial hardships brought on by cancer treatments.

One long-term strategy would be to invest in prevention, she writes. For immediate action, she says Medicare should be able to negotiate cancer drug prices or pay for the least costly alternative if the outcome is known to be about the same.

Other than that, Bradley says doctors should talk to their patients about costs and how much the patient would be expected to pay.

"They need to understand how much this is going to cost them and their families. They need to make an informed decision," Bradley told Reuters Health.

In her commentary, Bradley notes that eight-weeks of chemotherapy can exceed $30,000.

From their survey, Shankaran and her colleagues found only 42 percent of patients recalled talking about costs with their doctors.

"I think there are a lot of barriers," she said. "People may be embarrassed and they think the doctors shouldn't have to worry about this."

She added that patients may even think doctors might change their treatment recommendation if they mention costs.

"You wished they would have said something, because there are things we can do," Shankaran said.

Bradley believes the problem should be addressed through policy.

"I think this is a policy question, and the individual is caught in the middle… and I don't think there is much they can do about it."

However, Shankaran said, most oncologists have a financial counselor available in their offices and there are also resources available online.

SOURCE: and Journal of Clinical Oncology, online March 12, 2012.

• A Permanent Economic Emergency