The Russian-built Soyuz TMA-07M lifted off on time, at 1212 GMT, from Russia's Baikonur cosmodrome in Kazakhstan.
On the crew's two-day trip to the ISS, Canadian Chris Hadfield is joined by U.S. astronaut Tom Mashburn and Russian cosmonaut Roman Romanenko.
They will join U.S. astronaut Kevin Ford and Russians Oleg Novitsky and Yevgeny Tarelkin, who have been manning the $100-billion, 15-nation research complex since October.
(Reporting by Dmitry Solovyov; Editing by Alison Williams)
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